Fact Sheets and Documents

Considerations for the Implementation of Point of Care Tests (POC) for Syphilis

POC tests for syphilis differs from the traditional laboratory-based serologic testing primarily in specimen collection, time to result, need for confirmation, and sensitivity/specificity. While POC tests offers rapid results using whole blood from a fingerstick, it lacks the comprehensive assessment provided by laboratory-based tests, requiring confirmation and follow-up. It also underscores that laboratory-based testing remains the preferred option, particularly for individuals with a history of syphilis and low-risk individuals. Despite lower sensitivity and specificity, POC tests can be valuable, especially in settings with high incidence rates or where access to healthcare is limited.

Created by National Syphilis & Congenital Syphilis Syndemic Federal Task Force